Coronavirus disease 2019 (COVID-19): current status and future perspectives
Identifieur interne : 000769 ( 2020/Analysis ); précédent : 000768; suivant : 000770Coronavirus disease 2019 (COVID-19): current status and future perspectives
Auteurs : Heng Li [République populaire de Chine] ; Shang-Ming Liu [République populaire de Chine] ; Xiao-Hua Yu [République populaire de Chine] ; Shi-Lin Tang [République populaire de Chine] ; Chao-Ke Tang [République populaire de Chine]Source :
- International Journal of Antimicrobial Agents [ 0924-8579 ] ; 2020.
Abstract
As of 3 March 2020, COVID-19 has spread rapidly in 46 countries, causing >90 000 confirmed cases and >2946 deaths. Detection methods for SARS-CoV-2 include RT-qPCR and SHERLOCK technique. Four structural proteins are essential for SARS-CoV-2 assembly and infection, comprising the S, M, E and N proteins. Pangolin may be a potential intermediate host for SARS-CoV-2. Antiviral therapy, cellular therapy, immunotherapy and Chinese medicine may be promising therapeutic strategies.
Url:
DOI: 10.1016/j.ijantimicag.2020.105951
PubMed: 32234466
PubMed Central: 7139247
Affiliations:
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Province Cooperative Innovation Center for Molecular Target New Drug Study, Hengyang Medical College, University of South China, Hengyang, Hunan 421001, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, Department of Intensive Care Unit, the First Affiliated Hospital of University of South China, Medical Research Experiment Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Hengyang Medical College, University of South China, Hengyang, Hunan 421001</wicri:regionArea><wicri:noRegion>Hunan 421001</wicri:noRegion></affiliation></author><author><name sortKey="Liu, Shang Ming" sort="Liu, Shang Ming" uniqKey="Liu S" first="Shang-Ming" last="Liu">Shang-Ming Liu</name><affiliation wicri:level="1"><nlm:aff id="aff0001">Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, Department of Intensive Care Unit, the First Affiliated Hospital of University of South China, Medical Research Experiment Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Hengyang Medical College, University of South China, Hengyang, Hunan 421001, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, Department of Intensive Care Unit, the First Affiliated Hospital of University of South China, Medical Research Experiment Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Hengyang Medical College, University of South China, Hengyang, Hunan 421001</wicri:regionArea><wicri:noRegion>Hunan 421001</wicri:noRegion></affiliation></author><author><name sortKey="Yu, Xiao Hua" sort="Yu, Xiao Hua" uniqKey="Yu X" first="Xiao-Hua" last="Yu">Xiao-Hua Yu</name><affiliation wicri:level="1"><nlm:aff 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China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, Department of Intensive Care Unit, the First Affiliated Hospital of University of South China, Medical Research Experiment Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Hengyang Medical College, University of South China, Hengyang, Hunan 421001</wicri:regionArea><wicri:noRegion>Hunan 421001</wicri:noRegion></affiliation></author><author><name sortKey="Tang, Chao Ke" sort="Tang, Chao Ke" uniqKey="Tang C" first="Chao-Ke" last="Tang">Chao-Ke Tang</name><affiliation wicri:level="1"><nlm:aff id="aff0001">Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, Department of Intensive Care Unit, the First Affiliated Hospital of University of South China, Medical Research Experiment Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Hengyang Medical College, University of South China, Hengyang, Hunan 421001, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, Department of Intensive Care Unit, the First Affiliated Hospital of University of South China, Medical Research Experiment Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Hengyang Medical College, University of South China, Hengyang, Hunan 421001</wicri:regionArea><wicri:noRegion>Hunan 421001</wicri:noRegion></affiliation></author></analytic><series><title level="j">International Journal of Antimicrobial Agents</title><idno type="ISSN">0924-8579</idno><idno type="eISSN">1872-7913</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Highlights</title><p><list list-type="simple" id="celist0001"><list-item id="celistitem0001"><label>•</label><p id="para0002">As of 3 March 2020, COVID-19 has spread rapidly in 46 countries, causing >90 000 confirmed cases and >2946 deaths.</p></list-item><list-item id="celistitem0002"><label>•</label><p id="para0003">Detection methods for SARS-CoV-2 include RT-qPCR and SHERLOCK technique.</p></list-item><list-item id="celistitem0003"><label>•</label><p id="para0004">Four structural proteins are essential for SARS-CoV-2 assembly and infection, comprising the S, M, E and N proteins.</p></list-item><list-item id="celistitem0004"><label>•</label><p id="para0005">Pangolin may be a potential intermediate host for SARS-CoV-2.</p></list-item><list-item id="celistitem0005"><label>•</label><p 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